Anti-neuroinflammatory Activity of Elephantopus scaber L. via Activation of Nrf2/HO-1 Signaling and Inhibition of p38 MAPK Pathway in LPS-Induced Microglia BV-2 Cells

Anti-neuroinflammatory Activity of Elephantopus scaber L. via Activation of Nrf2/HO-1 Signaling and Inhibition of p38 MAPK Pathway in LPS-Induced Microglia BV-2 Cells

Elephantopus scaber L. (family: Asteraceae) has been traditionally utilized as a folkloric medicine and scientifically shown to exhibit anti-inflammatory activities in various in vivo inflammatory models. Given the lack of study on the effect of E. scaber in neuroinflammation, this study aimed to in...

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Bibliographic Details
Main Authors: Chim-Kei Chan, Loh Teng-Hern Tan, Shathiswaran N. Andy, Muhamad Noor Alfarizal Kamarudin, Bey-Hing Goh, Habsah Abdul Kadir
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Pharmacology
Subjects:
Elephantopus scaber L.
antioxidant
anti-inflammatory
Nrf2
NF-κB
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00397/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00397/full

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