Blocking the CXCL1-CXCR2 axis enhances the effects of doxorubicin in HCC by remodelling the tumour microenvironment via the NF-κB/IL-1β/CXCL1 signalling pathway

Abstract Inflammation is a core mechanism for oncogenesis. Chemokines act as important mediators of chronic inflammation and the tumour inflammatory response. However, there is limited information on chemokines in hepatocellular carcinoma (HCC), a disease for which almost all cases are derived from...

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Hlavní autoři: Huiyong Zhao, Sheng Wei, Dachen Zhou, Yongfan Liu, Zicheng Guo, Chuibao Fang, Xiaoxi Pang, Fei Li, Hui Hou, Xiao Cui
Médium: Článek
Jazyk:English
Vydáno: Nature Publishing Group 2023-04-01
Edice:Cell Death Discovery
On-line přístup:https://doi.org/10.1038/s41420-023-01424-y