Oxidative stress-induced endothelial cells-derived exosomes accelerate skin flap survival through Lnc NEAT1-mediated promotion of endothelial progenitor cell function

Oxidative stress-induced endothelial cells-derived exosomes accelerate skin flap survival through Lnc NEAT1-mediated promotion of endothelial progenitor cell function

Abstract Background Flap transplantation is commonly used in reconstructive surgery. A prerequisite for skin flap survival is sufficient blood supply. However, such approaches remain unclear. This study aimed to explore the underlying mechanisms of exosomes derived from human umbilical vascular endo...

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Bibliographic Details
Main Authors: Linlin Guo, Yuxuan Chen, Xiaoling Feng, Di Sun, Jiaming Sun, Shan Mou, Kangcheng Zhao, Ran An
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Stem Cell Research & Therapy
Subjects:
Oxidative stress
Exosomes
Endothelial progenitor cells
Angiogenesis
Lnc NEAT1
Skin flap
Online Access:https://doi.org/10.1186/s13287-022-03013-9

Internet

https://doi.org/10.1186/s13287-022-03013-9

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