Skeletal overgrowth in a pre-pubescent child treated with pan-FGFR inhibitor

Skeletal overgrowth in a pre-pubescent child treated with pan-FGFR inhibitor

Fibroblast growth factors and their receptors (FGFR) have major roles in both human growth and oncogenesis. In adults, therapeutic FGFR inhibitors have been successful against tumors that carry somatic FGFR mutations. In pediatric patients, trials testing these anti-tumor FGFR inhibitor therapeutics...

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Bibliographic Details
Main Authors: Fataneh Majlessipour, Gaohui Zhu, Nicole Baca, Meenasri Kumbaji, Vivian Hwa, Moise Danielpour
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Heliyon
Subjects:
Skeletal overgrowth
Fibroblast growth factor receptor
Fibroblast growth factor receptor inhibitor
Neuroglial tumor
Insulin-like growth factor
Skeletal dysplasia
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024069184

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http://www.sciencedirect.com/science/article/pii/S2405844024069184

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