Establishment of developmental gene silencing by ordered polycomb complex recruitment in early zebrafish embryos

Establishment of developmental gene silencing by ordered polycomb complex recruitment in early zebrafish embryos

Vertebrate embryos achieve developmental competency during zygotic genome activation (ZGA) by establishing chromatin states that silence yet poise developmental genes for subsequent lineage-specific activation. Here, we reveal the order of chromatin states in establishing developmental gene poising...

Full description

Bibliographic Details
Main Authors: Graham JM Hickey, Candice L Wike, Xichen Nie, Yixuan Guo, Mengyao Tan, Patrick J Murphy, Bradley R Cairns
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-01-01
Series:eLife
Subjects:
chromatin
polycomb
ubiquitylation
Placeholder
zygotic genome activation
development
Online Access:https://elifesciences.org/articles/67738

Internet

https://elifesciences.org/articles/67738

Similar Items