HSP27 Attenuates cGAS-Mediated IFN-β Signaling through Ubiquitination of cGAS and Promotes PRV Infection

HSP27 Attenuates cGAS-Mediated IFN-β Signaling through Ubiquitination of cGAS and Promotes PRV Infection

Pseudorabies (PR) is a domestic and wild animal infectious disease caused by the pseudorabies virus (PRV) and is one of the major infectious diseases that endanger the global swine industry. Studies have reported that PRV may achieve cross-species transmission from pigs to humans in recent years. Th...

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Bibliographic Details
Main Authors: Xiangrong Li, Jingying Xie, Dianyu Li, Hongshan Li, Yuhui Niu, Bei Wu, Yanmei Yang, Zhenfang Yan, Xiangbo Zhang, Lei Chen, Ruofei Feng
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Viruses
Subjects:
pseudorabies virus
heat shock protein 27
cyclic GMP-AMP synthase
cGAS-STING signaling pathway
ubiquitination
Online Access:https://www.mdpi.com/1999-4915/14/9/1851

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https://www.mdpi.com/1999-4915/14/9/1851

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