Comparative transcriptomic analysis of SARS-CoV-2 infected cell model systems reveals differential innate immune responses

Abstract The transcriptome of SARS-CoV-2-infected cells that reflects the interplay between host and virus has provided valuable insights into mechanisms underlying SARS-CoV-2 infection and COVID-19 disease progression. In this study, we show that SARS-CoV-2 can establish a robust infection in HEK29...

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Bibliographic Details
Main Authors: Guihua Sun, Qi Cui, Gustavo Garcia, Cheng Wang, Mingzi Zhang, Vaithilingaraja Arumugaswami, Arthur D. Riggs, Yanhong Shi
Format: Article
Language:English
Published: Nature Portfolio 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-96462-w