Chimeric RNA Design Principles for RNA-Mediated Gene Fusion
One common genetic alteration in cancer is gene fusion resulting from chromosomal translocations. The mechanisms that create such oncogenic fusion genes are not well understood. Previously, we provided the direct evidence that expression of a designed chimeric RNA can drive the formation of TMPRSS2-...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-03-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/11/6/1002 |