Synthesis of <i>N</i>-Substituted Iminosugar <i>C</i>-Glycosides and Evaluation as Promising <i>α</i>-Glucosidase Inhibitors

Synthesis of <i>N</i>-Substituted Iminosugar <i>C</i>-Glycosides and Evaluation as Promising <i>α</i>-Glucosidase Inhibitors

A series of <i>N</i>-substituted iminosugar <i>C</i>-glycosides were synthesized and tested for <i>α</i>-glucosidase inhibition. The results suggested that <b>6e</b> is a promising and potent <i>α</i>-glucosidase inhibitor. Enzymatic kineti...

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Bibliographic Details
Main Authors: Haibo Wang, Senling Tang, Guoqing Zhang, Yang Pan, Wei Jiao, Huawu Shao
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Molecules
Subjects:
iminosugars
<i>C</i>-glycosides
<i>α</i>-glucosidase
inhibitors
Online Access:https://www.mdpi.com/1420-3049/27/17/5517

Internet

https://www.mdpi.com/1420-3049/27/17/5517

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