A Bayesian network approach incorporating imputation of missing data enables exploratory analysis of complex causal biological relationships.

Bayesian networks can be used to identify possible causal relationships between variables based on their conditional dependencies and independencies, which can be particularly useful in complex biological scenarios with many measured variables. Here we propose two improvements to an existing method...

Full description

Bibliographic Details
Main Authors: Richard Howey, Alexander D Clark, Najib Naamane, Louise N Reynard, Arthur G Pratt, Heather J Cordell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-09-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009811