H7N9 bearing a mutation in the nucleoprotein leads to increased pathology in chickens

H7N9 bearing a mutation in the nucleoprotein leads to increased pathology in chickens

The zoonotic H7N9 avian influenza (AI) virus first emerged in 2013 as a low pathogenic (LPAI) strain, and has repeatedly caused human infection resulting in severe respiratory illness and a mortality of ~39% (>600 deaths) across five epidemic waves. This virus has circulated in poultry with l...

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Bibliographic Details
Main Authors: Daniel S. Layton, Jeffrey Butler, Cameron Stewart, Vicky Stevens, Jean Payne, Christina Rootes, Celine Deffrasnes, Som Walker, Songhua Shan, Tamara J. Gough, Christopher Cowled, Kerri Bruce, Jianning Wang, Katherine Kedzierska, Frank Y. K. Wong, Andrew G. D. Bean, John Bingham, David T. Williams
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
interferon
influenza
Mutation
T cell
H7N9
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.974210/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.974210/full

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