Preparation and effect of lyophilized platelet-rich fibrin on the osteogenic potential of bone marrow mesenchymal stem cells in vitro and in vivo

Objectives: The goal of this study was to prepare lyophilized platelet-rich fibrin (L-PRF) and analyze the combined use of L-PRF and osteogenic bone marrow mesenchymal stem cell (BMSC) sheet fragments for bone tissue engineering via in vivo injection. Methods: First, fresh PRF (F-PRF) was lyophilize...

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Bibliographic Details
Main Authors: Zhifa Wang, Leng Han, Tianyu Sun, Weijian Wang, Xiao Li, Buling Wu
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844019363996