Aryl hydrocarbon receptor activation-mediated vascular toxicity of ambient fine particulate matter: contribution of polycyclic aromatic hydrocarbons and osteopontin as a biomarker

Aryl hydrocarbon receptor activation-mediated vascular toxicity of ambient fine particulate matter: contribution of polycyclic aromatic hydrocarbons and osteopontin as a biomarker

Abstract Background Exposure to ambient fine particulate matter (PM2.5) is associated with vascular diseases. Polycyclic aromatic hydrocarbons (PAHs) in PM2.5 are highly hazardous; however, the contribution of PM2.5-bound PAHs to PM2.5-associated vascular diseases remains unclear. The ToxCast high-t...

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Bibliographic Details
Main Authors: Chia-Chi Ho, Wei-Te Wu, Yi-Jun Lin, Chen-Yi Weng, Ming-Hsien Tsai, Hui-Ti Tsai, Yu-Cheng Chen, Shaw-Fang Yet, Pinpin Lin
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Particle and Fibre Toxicology
Subjects:
Ambient particulate matter
VSMC migration
Osteopontin
Aryl hydrocarbon receptor
Polycyclic aromatic hydrocarbons
Biomarker
Online Access:https://doi.org/10.1186/s12989-022-00482-x

Internet

https://doi.org/10.1186/s12989-022-00482-x

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