Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1): a target for cancer therapeutic intervention?

Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1): a target for cancer therapeutic intervention?

Abstract Background Cap-dependent mRNA translation is essential for the translation of key oncogenic proteins at optimal levels and is highly regulated by the rate limiting, initiation step in protein synthesis. Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1) serves as a scaffold for ass...

Full description

Bibliographic Details
Main Authors: Praveen Kumar Jaiswal, Sweaty Koul, Nallasivam Palanisamy, Hari K. Koul
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Cancer Cell International
Subjects:
Cap-dependent translation
EIF4G1
TMA
TCGA
DepMap
EIF4G complex inhibitor
Online Access:http://link.springer.com/article/10.1186/s12935-019-0947-2

Internet

http://link.springer.com/article/10.1186/s12935-019-0947-2

Similar Items