Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1): a target for cancer therapeutic intervention?
Abstract Background Cap-dependent mRNA translation is essential for the translation of key oncogenic proteins at optimal levels and is highly regulated by the rate limiting, initiation step in protein synthesis. Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1) serves as a scaffold for ass...
Main Authors: | Praveen Kumar Jaiswal, Sweaty Koul, Nallasivam Palanisamy, Hari K. Koul |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-08-01
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Series: | Cancer Cell International |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12935-019-0947-2 |
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