Increased Plasma Levels of Adenylate Cyclase 8 and cAMP Are Associated with Obesity and Type 2 Diabetes: Results from a Cross-Sectional Study

Increased Plasma Levels of Adenylate Cyclase 8 and cAMP Are Associated with Obesity and Type 2 Diabetes: Results from a Cross-Sectional Study

Adenylate cyclases (ADCYs) catalyze the conversion of ATP to cAMP, an important co-factor in energy homeostasis. Giving ADCYs role in obesity, diabetes and inflammation, we questioned whether calcium-stimulated ADCY isoforms may be variably detectable in human plasma. We report the results of a cros...

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Bibliographic Details
Main Authors: Samy M. Abdel-Halim, Ashraf Al Madhoun, Rasheeba Nizam, Motasem Melhem, Preethi Cherian, Irina Al-Khairi, Dania Haddad, Mohamed Abu-Farha, Jehad Abubaker, Milad S. Bitar, Fahd Al-Mulla
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Biology
Subjects:
adenylate cyclase 8
ADCY8
ADCY3
ADCY1
Type 2 diabetes
obesity
Online Access:https://www.mdpi.com/2079-7737/9/9/244

Internet

https://www.mdpi.com/2079-7737/9/9/244

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