Menthol- and thymol-based ciprofloxacin derivatives against Mycobacterium tuberculosis: in vitro activity, lipophilicity, and computational studies
Abstract In this work, we investigated the antitubercular properties of Ciprofloxacin derivatives conjugated with menthol and thymol moieties. For the sixteen derivatives, we established minimal inhibitory concentrations (MIC) using isolates of Mycobacterium tuberculosis that were resistant or susce...
المؤلفون الرئيسيون: | , , , , , , , , , |
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التنسيق: | مقال |
اللغة: | English |
منشور في: |
Nature Portfolio
2023-09-01
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سلاسل: | Scientific Reports |
الوصول للمادة أونلاين: | https://doi.org/10.1038/s41598-023-43708-4 |