A new self-emulsifying formulation of mefenamic acid with enhanced drug dissolution

To enhance the dissolution of poorly soluble mefenamic acid, self-emulsifying formulation (SEF), composing of oil, surfactant and co-surfactant, was formulated. Among the oils and surfactants studied, Imwitor® 742, Tween® 60, Cremophore® EL and Transcutol® HP were selected as they showed maximal sol...

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Bibliographic Details
Main Authors: Pornsak Sriamornsak, Sontaya Limmatvapirat, Suchada Piriyaprasarth, Punyanutch Mansukmanee, Zongkang Huang
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087614000968