Saffron regulates bile acid metabolism and participates in the molecular mechanisms of cholestasis-induced liver injury through the mediation of the ERK signaling pathway

Saffron regulates bile acid metabolism and participates in the molecular mechanisms of cholestasis-induced liver injury through the mediation of the ERK signaling pathway

Bilirubin-induced liver injury is a severe health issue with inadequate treatment. This study examined whether saffron's Crocin and Crocetin could reduce bile stasis-induced liver injury. This study also investigated how these compounds may affect bile acid metabolism by inhibiting ERK phosphor...

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Bibliographic Details
Main Authors: Wenxiang Wang, Wei Xiong, Ning Li, Jing Xia, Ce Yang, Shu Xiong, Xuesong Deng
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Journal of Functional Foods
Subjects:
Cholestatic liver injury
Saffron
Crocin
Crocetin
p-ERK
PPARα
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464623005327

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http://www.sciencedirect.com/science/article/pii/S1756464623005327

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