Assessment of artemisinin tolerance in Plasmodium falciparum clinical isolates in children with uncomplicated malaria in Ghana

Assessment of artemisinin tolerance in Plasmodium falciparum clinical isolates in children with uncomplicated malaria in Ghana

Abstract Background Artemisinin-based combination therapy (ACT) is the first-line treatment for uncomplicated malaria in Ghana. Artemisinin (ART) tolerance in Plasmodium falciparum has arisen in Southeast Asia and recently, in parts of East Africa. This is ascribed to the survival of ring-stage para...

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Bibliographic Details
Main Authors: Samuel Yao Ahorhorlu, Neils Ben Quashie, Rasmus Weisel Jensen, William Kudzi, Edmund Tetteh Nartey, Nancy Odurowah Duah-Quashie, Felix Zoiku, Bartholomew Dzudzor, Christian William Wang, Helle Hansson, Michael Alifrangis, George Obeng Adjei
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Malaria Journal
Subjects:
Artemisinin tolerance
Plasmodium falciparum
Uncomplicated Malaria
Ex vivo ring-stage survival assay
Kelch 13
Pfcoronin
Online Access:https://doi.org/10.1186/s12936-023-04482-w

Internet

https://doi.org/10.1186/s12936-023-04482-w

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