Pyrrolidine dithiocarbamate ameliorates rotenone-induced Parkinson’s disease in rats

Pyrrolidine dithiocarbamate ameliorates rotenone-induced Parkinson’s disease in rats

Pyrrolidine dithiocarbamate (PDTC), a low-molecular-weight thiol antioxidant, possesses neuroprotection; however, its possible modulatory effect in Parkinson’s disease (PD) has not been tested. Male Wistar rats were injected with rotenone to induce PD-like symptoms. Histopathological findings showed...

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Bibliographic Details
Main Authors: Noha F. Abdelkader, Nadia M. Arafa, Amina S. Attia, Afaf A. Ain-Shoka, Dalaal M. Abdallah
Format: Article
Language:English
Published: Faculty of Pharmacy, Cairo University 2017-06-01
Series:Bulletin of Faculty of Pharmacy Cairo University
Subjects:
Pyrrolidine dithiocarbamate
Rotenone
Parkinson’s disease
Inflammation
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S1110093116300503

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http://www.sciencedirect.com/science/article/pii/S1110093116300503

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