Study of hesperetin effect on modulating transcription levels of MLH1 and MSH2 genes in SKBR3 breast cancer cell line

Study of hesperetin effect on modulating transcription levels of MLH1 and MSH2 genes in SKBR3 breast cancer cell line

Hesperetin (HSP), a flavonoid, has been validated to modify gene expression and function as an epigenetic agent to stop the development of breast carcinoma cells. HSP was investigated in this research to evaluate the expression of the MLH1 and MSH2 genes in cancerous breast cell lines (SKBR3) and he...

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Bibliographic Details
Main Authors: Naser Hameed Saleh, Ahmed Salim Kadhim Al-Khafaji, Esmaeil Babaei
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Journal of Advanced Pharmaceutical Technology & Research
Subjects:
3-(4
5-dimethylthiazol-2-yl)-2
5-diphenyltetrazolium bromide test
apoptosis
cytotoxicity
flow cytometry
half-maximal inhibitory concentration 50
hesperetin
malignancy
mlh1 gene expression
msh2 gene expression
Online Access:http://www.japtr.org/article.asp?issn=2231-4040;year=2023;volume=14;issue=4;spage=338;epage=344;aulast=Saleh

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http://www.japtr.org/article.asp?issn=2231-4040;year=2023;volume=14;issue=4;spage=338;epage=344;aulast=Saleh

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