JAK inhibitors in lichen planus: a review of pathogenesis and treatments

JAK inhibitors in lichen planus: a review of pathogenesis and treatments

Lichen planus (LP) is an auto-inflammatory skin disorder identified by a presence of T-cell lymphocytes at the dermal-epidermal junction. It is hypothesized that the INF–γ/CXCL10 axis fulfills a major role in the onset and persistence of chronic inflammation in LP. Since Janus kinases (JAKs) are inv...

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Bibliographic Details
Main Authors: Ali Motamed-Sanaye, Yasaman Fatemeh Khazaee, Motahareh Shokrgozar, Maryam Alishahi, Najmeh Ahramiyanpour, Maliheh Amani
Format: Article
Language:English
Published: Taylor & Francis Group 2022-11-01
Series:Journal of Dermatological Treatment
Subjects:
lichen planus
jak inhibitors
jak pathway
tofacitinib
barcitinib
upadacitinib
ruxolitinib
Online Access:http://dx.doi.org/10.1080/09546634.2022.2116926

Internet

http://dx.doi.org/10.1080/09546634.2022.2116926

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