The kinesin of the flagellum attachment zone in Leishmania is required for cell morphogenesis, cell division and virulence in the mammalian host.

Leishmania parasites possess a unique and complex cytoskeletal structure termed flagellum attachment zone (FAZ) connecting the base of the flagellum to one side of the flagellar pocket (FP), an invagination of the cell body membrane and the sole site for endocytosis and exocytosis. This structure is...

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Bibliographic Details
Main Authors: Rosa Milagros Corrales, Slavica Vaselek, Rachel Neish, Laurence Berry, Camille D Brunet, Lucien Crobu, Nada Kuk, Julio Mateos-Langerak, Derrick R Robinson, Petr Volf, Jeremy C Mottram, Yvon Sterkers, Patrick Bastien
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009666