A signature of saliva-derived exosomal small RNAs as predicting biomarker for esophageal carcinoma: a multicenter prospective study

A signature of saliva-derived exosomal small RNAs as predicting biomarker for esophageal carcinoma: a multicenter prospective study

Abstract Background The tRNA-derived small RNAs (tsRNAs) are produced in a nuclease-dependent manner in responses to variety of stresses that are common in cancers. We focus on a cancer-enriched tsRNA signature to develop a salivary exosome-based non-invasive biomarker for human esophageal squamous...

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Bibliographic Details
Main Authors: Kai Li, Yusheng Lin, Yichen Luo, Xiao Xiong, Lu Wang, Kameron Durante, Junkuo Li, Fuyou Zhou, Yi Guo, Shaobin Chen, Yuping Chen, Dianzheng Zhang, Sai-Ching Jim Yeung, Hao Zhang
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Molecular Cancer
Subjects:
Transfer RNA-derived small RNA
tRNA-derived fragments
Sequencing of salivary extracellular vesicles
Liquid-biopsy signature
Pre-operative biomarker of adjuvant therapy
Esophageal carcinoma
Online Access:https://doi.org/10.1186/s12943-022-01499-8

Internet

https://doi.org/10.1186/s12943-022-01499-8

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