Inositol-requiring enzyme 1α and c-Jun N-terminal kinase axis activation contributes to intracellular lipid accumulation in calf hepatocytes

Inositol-requiring enzyme 1α and c-Jun N-terminal kinase axis activation contributes to intracellular lipid accumulation in calf hepatocytes

ABSTRACT: During the perinatal period, dairy cows undergo negative energy balance, resulting in elevated circulating levels of nonesterified fatty acids (NEFA). Although increased blood NEFA concentrations are a physiological adaptation of early lactation, excessive NEFA in dairy cows is a major cau...

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Bibliographic Details
Main Authors: Wenwen Gao, Yanxi Wang, Siyu Liu, Guojin Li, Qi Shao, Cai Zhang, Liguang Cao, Kai Liu, Wenrui Gao, Zifeng Yang, Yifei Dong, Xiliang Du, Lin Lei, Guowen Liu, Xinwei Li
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Journal of Dairy Science
Subjects:
fatty liver
c-Jun N-terminal kinase
inositol-requiring enzyme 1α
hepatic lipid metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S0022030223007786

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http://www.sciencedirect.com/science/article/pii/S0022030223007786

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