Statins Lower Lipid Synthesis But Promote Secretion of Cholesterol-Enriched Extracellular Vesicles and Particles

Statins Lower Lipid Synthesis But Promote Secretion of Cholesterol-Enriched Extracellular Vesicles and Particles

Lipid droplets are lipid-rich cytosolic organelles that play roles in cell signaling, membrane trafficking, and many other cellular activities. Recent studies revealed that lipid droplets in cancer cells have various biological functions, such as energy production, membrane synthesis, and chemoresis...

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Bibliographic Details
Main Authors: Yundi Chen, Yongrui Xu, Jing Wang, Peter Prisinzano, Yuhao Yuan, Fake Lu, Mingfeng Zheng, Wenjun Mao, Yuan Wan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Oncology
Subjects:
extracellular vesicles and particles
statins
cholesterol
lipidomics
ovarian cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.853063/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.853063/full

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