Hypoxia Induces Saturated Fatty Acids Accumulation and Reduces Unsaturated Fatty Acids Independently of Reverse Tricarboxylic Acid Cycle in L6 Myotubes

Obstructive sleep apnea syndrome, characterized by repetitive episodes of tissue hypoxia, is associated with several metabolic impairments. Role of fatty acids and lipids attracts attention in its pathogenesis for their metabolic effects. Parallelly, hypoxia-induced activation of reverse tricarboxyl...

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Main Authors: Lukas Vacek, Ales Dvorak, Kamila Bechynska, Vit Kosek, Moustafa Elkalaf, Minh Duc Trinh, Ivana Fiserova, Katerina Pospisilova, Lucie Slovakova, Libor Vitek, Jana Hajslova, Jan Polak
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Endocrinology
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Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.663625/full