Next-Generation Sequencing-Based Quantitative Detection of Hepatitis B Virus Pre-S Mutants in Plasma Predicts Hepatocellular Carcinoma Recurrence

Next-Generation Sequencing-Based Quantitative Detection of Hepatitis B Virus Pre-S Mutants in Plasma Predicts Hepatocellular Carcinoma Recurrence

Hepatocellular carcinoma (HCC) is among the most common and lethal human cancers worldwide. Despite curative resection, high recurrence of HCC remains a big threat, leading to poor patient outcomes. Hepatitis B virus (HBV) pre-S mutants, which harbor deletions over pre-S1 and pre-S2 gene segments of...

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Bibliographic Details
Main Authors: Chiao-Fang Teng, Tsai-Chung Li, Hsi-Yuan Huang, Jia-Hui Lin, Wen-Shu Chen, Woei-Cherng Shyu, Han-Chieh Wu, Cheng-Yuan Peng, Ih-Jen Su, Long-Bin Jeng
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Viruses
Subjects:
hepatocellular carcinoma
hepatitis B virus
pre-S mutants
recurrence
next-generation sequencing
Online Access:https://www.mdpi.com/1999-4915/12/8/796

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https://www.mdpi.com/1999-4915/12/8/796

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