Human spermatozoa anti-proprotein convertase subtilisin/kexin type 4 synthesis using New Zealand rabbit for novel immunocontraception in males

Purpose: Proprotein convertase subtilisin/kexin type 4 (PCSK4, a 54-kDa protease) is expressed in the plasma membrane of the acrosome in human spermatozoa. It plays a critical role in penetrating the zona pellucida. Synthesis of human anti-PCSK4 might be important for novel male immunocontraception....

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Bibliographic Details
Main Authors: Dahril, Aulanni'am, Vivi Keumala, Akhmad Mustafa
Format: Article
Language:English
Published: Korean Urological Association 2019-07-01
Series:Investigative and Clinical Urology
Subjects:
Online Access:https://www.icurology.org/Synapse/Data/PDFData/2020ICU/icu-60-303.pdf