Insulin Downregulated the Infection of Uropathogenic <i>Escherichia coli</i> (UPEC) in Bladder Cells in a High-Glucose Environment through JAK/STAT Signaling Pathway

Insulin Downregulated the Infection of Uropathogenic <i>Escherichia coli</i> (UPEC) in Bladder Cells in a High-Glucose Environment through JAK/STAT Signaling Pathway

Diabetic individuals have a higher incidence of urinary tract infection (UTI) than non-diabetic individuals, and also require longer treatment. We evaluated the effects of insulin pretreatment on the regulation of JAK/STAT transduction pathways in UPEC-infected bladder cells in a high-glucose enviro...

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Bibliographic Details
Main Authors: Chen-Hsun Ho, Shih-Ping Liu, Chia-Kwung Fan, Kai-Yi Tzou, Chia-Chang Wu, Po-Ching Cheng
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Microorganisms
Subjects:
bladder cells
insulin
JAK/STAT
urinary tract pathogenic <i>Escherichia coli</i>
Online Access:https://www.mdpi.com/2076-2607/9/12/2421

Internet

https://www.mdpi.com/2076-2607/9/12/2421

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