Sexually dimorphic methylation patterns characterize the placenta and blood from extremely preterm newborns

Abstract Background Health outcomes among children born prematurely are known to be sexually dimorphic, with male infants often more affected, yet the mechanism behind this observation is not clear. CpG methylation levels in the placenta and blood also differ by sex and are associated with adverse h...

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Main Authors: Hudson P. Santos, Adam E. Enggasser, Jeliyah Clark, Kyle Roell, Vasyl Zhabotynsky, William Adam Gower, Diana Yanni, Nou Gao Yang, Lisa Washburn, Semsa Gogcu, Carmen J. Marsit, Karl Kuban, T. Michael O’Shea, Rebecca C. Fry
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Biology
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Online Access:https://doi.org/10.1186/s12915-023-01662-7