Tailoring Magnetite-Nanoparticle-Based Nanocarriers for Gene Delivery: Exploiting CRISPRa Potential in Reducing Conditions

Tailoring Magnetite-Nanoparticle-Based Nanocarriers for Gene Delivery: Exploiting CRISPRa Potential in Reducing Conditions

Gene delivery has emerged as a promising alternative to conventional treatment approaches, allowing for the manipulation of gene expression through gene insertion, deletion, or alteration. However, the susceptibility of gene delivery components to degradation and challenges associated with cell pene...

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Bibliographic Details
Main Authors: David Arango, Javier Cifuentes, Paola Ruiz Puentes, Tatiana Beltran, Amaury Bittar, Camila Ocasión, Carolina Muñoz-Camargo, Natasha I. Bloch, Luis H. Reyes, Juan C. Cruz
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Nanomaterials
Subjects:
gene delivery
CRISPRa
magnetite nanoparticles
disulfide bond
<i>pink1</i>
nanoconjugates
Online Access:https://www.mdpi.com/2079-4991/13/11/1782

Internet

https://www.mdpi.com/2079-4991/13/11/1782

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