The Promoter of the Immune-Modulating Gene <i>TIR-Containing Protein C</i> of the Uropathogenic <i>Escherichia coli</i> Strain CFT073 Reacts to the Pathogen’s Environment

The Promoter of the Immune-Modulating Gene <i>TIR-Containing Protein C</i> of the Uropathogenic <i>Escherichia coli</i> Strain CFT073 Reacts to the Pathogen’s Environment

The <i>TIR-containing protein C</i> (TcpC) of the uropathogenic <i>Escherichia coli</i> strain CFT073 modulates innate immunity by interfering with the Toll-like receptor and NALP3 inflammasome signaling cascade. During a urinary tract infection the pathogen encounters epithe...

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Bibliographic Details
Main Authors: Jacqueline Hemberger, Julia Ittensohn, Hannah Griffiths, Maren Keller, Victor Costina, Simone Albrecht, Thomas Miethke
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
uropathogenic <i>Escherichia coli</i>
TcpC
host cell
potassium
sodium
bacterial density
Online Access:https://www.mdpi.com/1422-0067/23/3/1148

Internet

https://www.mdpi.com/1422-0067/23/3/1148

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