Salinomycin effectively eliminates cancer stem-like cells and obviates hepatic metastasis in uveal melanoma

Salinomycin effectively eliminates cancer stem-like cells and obviates hepatic metastasis in uveal melanoma

Abstract Background Uveal melanoma (UM) is the most common primary intraocular tumor. Hepatic metastasis is the major and direct death-related reason in UM patients. Given that cancer stem-like cells (CSCs) are roots of metastasis, targeting CSCs may be a promising strategy to overcome hepatic metas...

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Bibliographic Details
Main Authors: Jingfeng Zhou, Shenglan Liu, Yun Wang, Wei Dai, Hailin Zou, Shubo Wang, Jing Zhang, Jingxuan Pan
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Molecular Cancer
Subjects:
Uveal melanoma
Salinomycin
Twist1
Cancer stem-like cells
Metastasis
Online Access:http://link.springer.com/article/10.1186/s12943-019-1068-1

Internet

http://link.springer.com/article/10.1186/s12943-019-1068-1

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