Erythropoietin overrides the triggering effect of DNA platination products in a mouse model of Cisplatin-induced neuropathy

Erythropoietin overrides the triggering effect of DNA platination products in a mouse model of Cisplatin-induced neuropathy

<p>Abstract</p> <p>Background</p> <p>Cisplatin mediates its antineoplastic activity by formation of distinct DNA intrastrand cross links. The clinical efficacy and desirable dose escalations of cisplatin are restricted by the accumulation of DNA lesions in dorsal root g...

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Bibliographic Details
Main Authors: Egensperger Rupert, Kribben Andreas, Dzagnidze Anna, Liedert Bernd, Schäfers Maria, Obermann Mark, Katsarava Zaza, Yoon Min-Suk, Limmroth Volker, Diener Hans-Christoph, Thomale Juergen
Format: Article
Language:English
Published: BMC 2009-07-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/10/77

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http://www.biomedcentral.com/1471-2202/10/77

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