Allantoin ameliorates chemically-induced pancreatic β-cell damage through activation of the imidazoline I3 receptors

Allantoin ameliorates chemically-induced pancreatic β-cell damage through activation of the imidazoline I3 receptors

Objective. Allantoin is the primary active compound in yams (Dioscorea spp.). Recently, allantoin has been demonstrated to activate imidazoline 3 (I3) receptors located in pancreatic tissues. Thus, the present study aimed to investigate the role of allantoin in the effect to improve damage induced i...

Full description

Bibliographic Details
Main Authors: Marie Amitani, Kai-Chun Cheng, Akihiro Asakawa, Haruka Amitani, Timothy Sean Kairupan, Nanami Sameshima, Toshiaki Shimizu, Teruto Hashiguchi, Akio Inui
Format: Article
Language:English
Published: PeerJ Inc. 2015-08-01
Series:PeerJ
Subjects:
Allantoin
Imidazoline 3 receptor
Pancreatic
PLC-related pathway
Streptozotocin
Online Access:https://peerj.com/articles/1105.pdf

Internet

https://peerj.com/articles/1105.pdf

Similar Items