Synthesis and antidiabetic activity of β-acetamido ketones
This paper reports the use of trifluoroacetic acid as a catalyst in the Dakin–West reaction for the synthesis of β-acetamido ketones. The method has several advantages such as requiring only mild conditions and a low concentration of catalyst. Screening of 19 β-acetamido ketones for antidiabetic act...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2011-08-01
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Series: | Acta Pharmaceutica Sinica B |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221138351100044X |