PD-1 inhibitors-based second-line therapy for metastatic gastric cancer

BackgroundMetastatic gastric cancer (MGC) patients with progression on first-line treatment still have poor outcomes on chemotherapy. The KEYNOTE-061 study demonstrated that pembrolizumab, a PD-1inhibitor, was not better than paclitaxel as second-line therapy for MGC. Herein, we explored the efficac...

Full description

Bibliographic Details
Main Authors: Miaomiao Gou, Yong Zhang, Zhikuan Wang, Guanghai Dai
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1136437/full