C‐C Chemokine Receptor Type 5 (CCR5)‐Mediated Docking of Transferred Tregs Protects Against Early Blood‐Brain Barrier Disruption After Stroke

C‐C Chemokine Receptor Type 5 (CCR5)‐Mediated Docking of Transferred Tregs Protects Against Early Blood‐Brain Barrier Disruption After Stroke

BackgroundDespite recent evidence demonstrating a potent protective effect of adoptively transferred regulatory T cells (Tregs) in ischemic stroke, the mechanism for Treg mobilization and activation in the ischemic brain is, remarkably, unknown. This study determines the role of C‐C chemokine recept...

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Bibliographic Details
Main Authors: Peiying Li, Long Wang, Yuxi Zhou, Yu Gan, Wen Zhu, Yuguo Xia, Xiaoyan Jiang, Simon Watkins, Alberto Vazquez, Angus W. Thomson, Jun Chen, Weifeng Yu, Xiaoming Hu
Format: Article
Language:English
Published: Wiley 2017-08-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
blood‐brain barrier
brain ischemia
stroke
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.117.006387

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.117.006387

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