Drug-Induced Oxidative Stress and Toxicity

Reactive oxygen species (ROS) are a byproduct of normal metabolism and have roles in cell signaling and homeostasis. Species include oxygen radicals and reactive nonradicals. Mechanisms exist that regulate cellular levels of ROS, as their reactive nature may otherwise cause damage to key cellular co...

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Bibliographic Details
Main Authors: Damian G. Deavall, Elizabeth A. Martin, Judith M. Horner, Ruth Roberts
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2012/645460