Piezo1 forms a slowly-inactivating mechanosensory channel in mouse embryonic stem cells

Piezo1 is a mechanosensitive (MS) ion channel with characteristic fast-inactivation kinetics. We found a slowly-inactivating MS current in mouse embryonic stem (mES) cells and characterized it throughout their differentiation into motor-neurons to investigate its components. MS currents were large a...

Full description

Bibliographic Details
Main Authors: Josefina Inés del Mármol, Kouki K Touhara, Gist Croft, Roderick MacKinnon
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/33149