Competitive aptamer switch for modulating ligand binding affinity

Aptamers are short, single-stranded DNA or RNA molecules that selectively bind to a target molecule. Aptamer-complement duplex (ACD) is often used to design molecular switches capable of producing a detectable signal or triggering a structural change upon aptamer binding to a target. However, such a...

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Bibliographic Details
Main Authors: Derek Puyat, Sung Won Oh, Shiming Liu, Jinglin Fu, Ph.D
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-09-01
Series:Advanced Agrochem
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S277323712300045X