Brazilin is a natural product inhibitor of the NLRP3 inflammasome

Brazilin is a natural product inhibitor of the NLRP3 inflammasome

Summary: Excessive or aberrant NLRP3 inflammasome activation has been implicated in the progression and initiation of many inflammatory conditions; however, currently no NLRP3 inflammasome inhibitors have been approved for therapeutic use in the clinic. Here we have identified that the natural produ...

Full description

Bibliographic Details
Main Authors: Emily McMahon, Sherihan El-Sayed, Jack Green, Christopher Hoyle, Lorna FitzPatrick, Emma V. Jones, Eve Corrie, Rebecca L. Kelly, Mairi Challinor, Sally Freeman, Richard A. Bryce, Catherine B. Lawrence, David Brough, Paul R. Kasher
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Biological sciences
Biochemistry
Biomolecules
Natural product biochemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224001895

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224001895

Similar Items