Donor-derived cytomegalovirus-cytotoxic T lymphocytes and leflunomide successfully control refractory cytomegalovirus infections and disease of multiple sites after allogeneic-hematopoietic stem cell transplantation: A case report

Donor-derived cytomegalovirus-cytotoxic T lymphocytes and leflunomide successfully control refractory cytomegalovirus infections and disease of multiple sites after allogeneic-hematopoietic stem cell transplantation: A case report

Drug-resistant cytomegalovirus (CMV) infection after hematopoietic stem cell transplantation (HSCT) often leads to morbidity and mortality. Several studies have shown that CMV-cytotoxic T lymphocytes (CTLs) can overcome drug-resistant CMV infection, but still many questions remain unanswered. Here,...

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Bibliographic Details
Main Authors: Nan Su, Zhenghua Liu, Peng Sun, Feng Gu, Xiaojing Yan, Dali Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Medicine
Subjects:
cytomegalovirus
CTLs
leflunomide
allo-HSCT
case report
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.948210/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.948210/full

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