Transmembrane collagen XVII modulates integrin dependent keratinocyte migration via PI3K/Rac1 signaling.

Transmembrane collagen XVII modulates integrin dependent keratinocyte migration via PI3K/Rac1 signaling.

The hemidesmosomal transmembrane component collagen XVII (ColXVII) plays an important role in the anchorage of the epidermis to the underlying basement membrane. However, this adhesion protein seems to be also involved in the regulation of keratinocyte migration, since its expression in these cells...

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Bibliographic Details
Main Authors: Stefanie Löffek, Tiina Hurskainen, Joanna Jackow, Florian Christoph Sigloch, Oliver Schilling, Kaisa Tasanen, Leena Bruckner-Tuderman, Claus-Werner Franzke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3914815?pdf=render

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http://europepmc.org/articles/PMC3914815?pdf=render

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