Safety Studies of Pneumococcal Endolysins Cpl-1 and Pal

Safety Studies of Pneumococcal Endolysins Cpl-1 and Pal

Bacteriophage-derived endolysins have gained increasing attention as potent antimicrobial agents and numerous publications document the in vivo efficacy of these enzymes in various rodent models. However, little has been documented about their safety and toxicity profiles. Here, we present preclinic...

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Bibliographic Details
Main Authors: Marek Harhala, Daniel C. Nelson, Paulina Miernikiewicz, Ryan D. Heselpoth, Beata Brzezicka, Joanna Majewska, Sara B. Linden, Xiaoran Shang, Aleksander Szymczak, Dorota Lecion, Karolina Marek-Bukowiec, Marlena Kłak, Bartosz Wojciechowicz, Karolina Lahutta, Andrzej Konieczny, Krystyna Dąbrowska
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Viruses
Subjects:
endolysin
Pal
Cpl-1
safety
toxicity
immune response
<i>Streptococcus pneumoniae</i>
Online Access:https://www.mdpi.com/1999-4915/10/11/638

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https://www.mdpi.com/1999-4915/10/11/638

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