Radiosynthesis of Stable <sup>198</sup>Au-Nanoparticles by Neutron Activation of α<sub>v</sub>β<sub>3</sub>-Specific AuNPs for Therapy of Tumor Angiogenesis

Radiosynthesis of Stable <sup>198</sup>Au-Nanoparticles by Neutron Activation of α<sub>v</sub>β<sub>3</sub>-Specific AuNPs for Therapy of Tumor Angiogenesis

This paper reports on the development of stable tumor-specific gold nanoparticles (AuNPs) activated by neutron irradiation as a therapeutic option for the treatment of cancer with high tumor angiogenesis. The AuNPs were designed with different mono- or dithiol-ligands and decorated with different am...

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Bibliographic Details
Main Authors: Güllü Davarci, Carmen Wängler, Klaus Eberhardt, Christopher Geppert, Ralf Schirrmacher, Robert Freudenberg, Marc Pretze, Björn Wängler
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Pharmaceuticals
Subjects:
gold nanoparticles
[<sup>198</sup>Au]AuNPs
radioactive
tumor therapy
tumor angiogenesis
RGD peptide
Online Access:https://www.mdpi.com/1424-8247/16/12/1670

Internet

https://www.mdpi.com/1424-8247/16/12/1670

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