Rheological effects of hypertonic saline and sodium bicarbonate solutions on cystic fibrosis sputum in vitro

Rheological effects of hypertonic saline and sodium bicarbonate solutions on cystic fibrosis sputum in vitro

Abstract Background Cystic fibrosis (CF) is a life-threatening multiorgan genetic disease, particularly affecting the lungs, where recurrent infections are the main cause of reduced life expectancy. In CF, mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR)...

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Main Authors: Mária Budai-Szűcs, Szilvia Berkó, Anita Kovács, Pongsiri Jaikumpun, Rita Ambrus, Adrien Halász, Piroska Szabó-Révész, Erzsébet Csányi, Ákos Zsembery
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Pulmonary Medicine
Subjects:
Cystic fibrosis
Rheology
Hypertonic salt solutions
Bicarbonate
In vitro treatment
Online Access:https://doi.org/10.1186/s12890-021-01599-z

Internet

https://doi.org/10.1186/s12890-021-01599-z

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