USP2 promotes experimental colitis and bacterial infections by inhibiting the proliferation of myeloid cells and remodeling the extracellular matrix network

USP2 promotes experimental colitis and bacterial infections by inhibiting the proliferation of myeloid cells and remodeling the extracellular matrix network

Inflammatory bowel disease (IBD) is closely associated with dysregulation of genetic factors and microbial environment. Here, we report a susceptible role of ubiquitin-specific protease 2 (USP2) in experimental colitis and bacterial infections. USP2 is upregulated in the inflamed mucosa of IBD patie...

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Bibliographic Details
Main Authors: Ran An, Peng Wang, Hao Guo, Tianzi Liuyu, Bo Zhong, Zhi-Dong Zhang
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Cell Insight
Subjects:
USP2
Colitis
Bacterial infection
Cell proliferation
Myeloid cells
Online Access:http://www.sciencedirect.com/science/article/pii/S277289272200044X

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http://www.sciencedirect.com/science/article/pii/S277289272200044X

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